Acid sphingomyelinase deficiency (ASMD) - A rare condition with a slight Middle Eastern link.
Orphan genetic diseases afflict a minimal number of people. Relatively rare, they still do affect millions of people, collectively contributing to Global disease burden. Studies conducted estimates that there are as many as 7,000 diseases that are designated as rare, and one out of 15 persons worldwide are estimated to be affected by a rare disease constituting 400 million people worldwide.
https://duphat.ae/A-rare-condition-with-a-slight-Middle-Eastern-link/
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